Modalert 200 's active component, modafinil, is liver-safe at recommended dosages. Using it as prescribed has not been demonstrated to cause liver damage in healthy people. Cytochrome P450 enzymes digest it. As with any drug, there may be fluctuations, and liver enzyme increase or damage have been occasional. People with liver illness or poor liver function should take Modalert 200 mg (or any modafinil) carefully. In therapy, a doctor may suggest dosage modifications or liver function monitoring. I
